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cross-protection against peroxide killing by a superoxide generator in Vibrio harveyi . FEMS Microbiol Lett 2003, 221:89–95.PubMedCrossRef Competing interests The authors declare that they have no competing interests. Authors’ contributions PP and NC designed the research. UB Adenosine triphosphate performed bioinformatics analysis of protein sequences. PP and ST constructed the mutant. PP and PP constructed the complementary strain. PP and BU carried out enzymatic activity assay. PP and VM carried out growth kinetic assay. PP and TS performed the colony examination. PP and PP carried out invasion and

survival assay. PP and MV performed the oxidative response experiment. PP carried out statistical analysis. PP wrote the manuscript. NC and KS critically revised the manuscript for intellectual content. All authors read and approved the final version of the manuscript.”
“Background Legionella pneumophila is a waterborne pathogen that can survive in a wide range of environmental conditions [1]. It is the etiological agent of Legionnaires’ disease, which can progress to fatal pneumonia [2]. Transmission between individuals is not observed, but aerosol transmission from the aquatic environment to humans is now well documented [1–4]. After inhalation and dissemination into the lungs, L. pneumophila invades alveolar macrophages where it multiplies intracellularly.