001). Seventy patients with initially unresectable CLM underwent liver resection after tumor downsizing by induction chemotherapy. Shifting of the CRS from high to low (8 patients; 11.4%) improved disease-free survival and overall survival.
Conclusion: High CRS is associated with worse survival after resection in resectable and unresectable disease. The CRS
may be used for risk assessment when recommending oncological surgical timing in initially unresectable disease and treatment options for perioperative or adjuvant treatment in resectable disease. (C) 2012 Elsevier Ltd. All rights reserved.”
“Our previous drift/diffusion model PFTα describing the effect of the transport and accumulation of copper ions on the time to failure of dielectrics was extended here to
include metallic barriers and the effect of an elastic drift term. The results of the model were compared with experimental data on the time to failure of SiO(2) dielectrics that included Ru(P) and TaN barriers. Excellent agreement was found, and the success of the Ru(P) compared to the TaN barrier was attributed to the former’s lower copper ion solubility and diffusivity. There is a change in the value of the field acceleration lparameter (gamma) with barriers that leads to an increase in the projected lifetime. We link this change in gamma to a number of factors including the transport of oxidizing species through the barrier responsible for copper ion formation, and the injection and motion of electrons and holes, PF-04929113 mw which are altered in the presence of a barrier between the metal and dielectric. (C) 2009 selleck products American Institute of Physics. [doi:10.1063/1.3238517]“
“In this study, we define the histopathological features of female urethral diverticula and attempt to elucidate its pathogenesis and etiology.
We analyzed 22 clinical
records of women diagnosed with urethral diverticula. We collected clinical, surgical, and pathological data. Pathological re-assessment was performed using hematoxylin-eosin and van Gieson stains.
The predominant epithelial types were squamous (41.9%), columnar (31.8%), combined squamous and columnar (18.2%), and cuboidal (13.6%). There was no case of the transitional type. Epithelial ulcerations were present in nine cases. The diverticular wall was composed only of fibrous collagen tissue in all cases. Inflammatory signs were noted in 77.3% of specimens.
Histopathological features of female urethral diverticula match the criteria for paraurethral cysts. Concomitant use of synthetic meshes should be avoided due to the possibility of an infectious etiology. Transvaginal excision of the sac is recommended, while transurethral procedures are contraindicated.”
“A passive probe antenna for cw near-field microscopy at millimeter and submillimeter wavelengths is defined. It is based on the coupling between a free-space linearly polarized propagating beam to a wire mode.