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“We describe a 23-year-old patient who presented acutely with haemophagocytic lymphohistiocytosis (HL) and Melkersson-Rosenthal syndrome (MRS). MRS and HL are two unusual and complex clinical patterns that may present acutely and to our knowledge, an association between them has never been reported. The clinical investigations in this patient led to identification of parvovirus B19 (PB19) viraemia by PCR. Parvovirus infection has been reported as a cause of virus-associated HL, but the presence of PB19 has never been sought or reported as a possible trigger for MRS. This observation suggests a possible association between PB19 and HL, and opens the possibility of its association

also selleck chemicals with acute-onset MRS. Further investigations for the presence

of PB19 in cases of MRS are warranted.”
“To investigate clinical characteristics of parvovirus (B19) related aplastic anemia (AA).\n\nOf the 28 children with AA included in this study, 24 were selleck compound treated routinely and received planned follow-up; 15 were subject to B19-DNA re-examination during the treatment and 8 underwent examination for B19-IgM and B19-IgG. Another 39 initially identified AA children were enrolled as the controls and received the treatment same as the above-mentioned group.\n\nThere were more patients aged 5-8 y in the B19 infection group than the control group (P < 0.05). The course of AA in the B19 infection group was less than 2 mo and the serious aplastic anemia (SAA) and very serious aplastic anemia (VSAA) were more frequently observed in this group than S3I-201 the controls (P < 0.05). The overall efficacy of the treatments in the B19 infection group was more dismal

than that in the controls (P < 0.05). Among 15 patients who were subjected to B19-DNA re-examination, negative findings were found in 6 patients with chronic aplastic anemia (CAA); the B19-DNA was persistently positive in 2 of the SAA and 5 VSAA patients. IgM and IgG were respectively detected in 3 and 2 patients out of the 8 children who received antibody examination.\n\nParvovirus B19 infection contributes to the generation of AA, particularly in children aged 5-8 y. The AA induced may be mainly classified as serious and very serious type, with a course of disease less than 2 mo. Patients can be saved if B19-DNA is eliminated and the antibody is produced.”
“A bioenergetic model of marine phase, wild Atlantic salmon was constructed to investigate the potential effects on post-smolt growth of predicted changes in oceanic conditions. Short-term estimates of growth in weight were similar to measurements in captivity and simulated growth varied with water temperature and swimming speed as expected. Longer-term estimates of growth in length were less than that achieved by wild salmon, particularly with constant swimming assumed. The model was sensitive to parameters relating to maximum daily food consumption.