The study is sponsored by the University Of Nottingham; neither the sponsor nor the funders will be involved in the analysis of study data

or report writing. QbTech will provide QbTest reports to the study team, which will be analysed by BG, from the University Of Nottingham. Only the research team will have access to the study data, data generated from the trial will www.selleckchem.com/products/BIBF1120.html be available for inspection by the ethics and R&D committees on request. Changes to the protocol will be communicated to the ethics committee by the lead research fellow (CLH). The process for obtaining participant informed consent or assent and parent/guardian informed consent will be in accordance with the ethical guidance, and Good Clinical Practice. The investigator or their nominee and the participant or other legally authorised representative (such as the child’s parent) shall sign and date the informed consent forms (see online

supplementary appendix A and B) before the person can participate in the study. Written consent will be required from young people aged 16 years and above and their parents. If the young person is under 16 years of age, parental consent will be required, with the young person’s written or verbal assent. Individual participant medical information obtained as a result of this study are considered confidential and disclosure to third parties is prohibited unless warranted by an adverse event. Participant confidentiality will be further ensured by utilising identification code numbers to correspond to treatment data in the computer files. No post-trial care is required. The primary aim of this study is to determine whether using QbTest in routine NHS settings can accelerate time to correct diagnosis, with a secondary aim of examining whether the QbTest can improve patient outcome. Currently, there are few trials conducted in routine NHS settings with the aim of improving the ADHD care pathway, despite evidence to suggest suboptimal care standards and rising socioeconomic burdens. The findings of this study will help to demonstrate whether the QbTest is clinically useful and financially viable in

standard care. The findings of the trial will be submitted for publication in appropriate journals regardless of outcome (in accordance with the recommendations of CONSORT) and to members of the GSK-3 public. Supplementary Material Author’s manuscript: Click here to view.(3.1M, pdf) Reviewer comments: Click here to view.(62K, pdf) Acknowledgments The authors would like to thank the site Principle Investigators: Adrian Williams (Alder Hey), Dr Kim Selby (Medway), Dr Samina Holsgrove (Central Manchester), Dr Ify Omeneka (Warrington), Dr Ann-Marie Skarstam (Sussex, Hastings), Dr Sarah Curran (Sussex, Maidstone), Dr Neeta Kulkarni (Leicester), Dr Julie Clarke (Lincoln), Dr Maria Moldavsky and Dr Dilip Nathan (Nottingham) for their support.