SJ acknowledges support by the Cluster of Excellence and DFG Research Center Nanoscale Microscopy and Molecular Physiology of the Brain. “
“The Publisher regrets that the paper “Lessons on the critical interplay between

zinc binding and protein structure and dynamics” was supposed to have been identified as an “”Early Career Focused Review”" when it was published in the April 2013 issue (121C). Also, the cover art of the current issue (123C) is from the above mentioned article which was intended to appear in the cover of April 2013 issue (Volume 121C). The publisher would like to apologize for any inconvenience Selleck GDC0199 caused. “
“Recently, loads on propellers have been increasing due to the need for large and high-speed ships. Therefore, propeller cavitation is increasing, and the resulting adverse effects are becoming an important issue. Cavitation on a propeller induces pressure fluctuations on the hull. The limitation of tip clearance and an increase in higher order pressure fluctuation can cause severe ship vibration and a noise problem. Therefore, a technique allowing for the prediction and control of pressure fluctuations induced by propeller cavitation is needed at the design stage. The factors causing pressure fluctuation induced by a propeller are classified into three

primary parts: changes in the blade loading, rotation of the blade thickness, and the volume change of the propeller cavitation (Carlton, 2007). However, pressure fluctuation due to changes in blade loading and blade thickness are very small compared with the pressure fluctuations caused by cavitation. Various types of propeller cavitation, such as sheet cavitation, tip vortex cavitation, and bubble R428 in vivo cavitation, affect the hull pressure fluctuation. The peak pressure fluctuation

is measured in a discrete form at the blade rate frequency and is caused by unsteady sheet cavitation (Carlton, 2007). There have been numerous studies of the pressure fluctuation either caused by propeller cavitation (Kinns and Bloor, 2004, Merz et al., 2009, Lee et al., 1992, Cavitation Committee Report, 1987 and The Specialist Committee on Cavitation Induced Pressures, 2002). In recent years numerical prediction method using CFD is introduced and it shows good results (Pereira et al., 2004, Ji et al., 2011, Ji et al., 2012, Kehr and Kao, 2011, Luo et al., 2012 and Seo et al., 2008). Most studies investigated the correlation between predictions, model test results, and real ship measurements (Kim et al., 1996). Recently, the potential-based numerical prediction methods have been introduced that consider the physical propeller configuration and operating conditions. However, these numerical prediction methods make it difficult to intuitively understand the governing equation because they are presented in a form that is a result of solving potential-based boundary value problems. Moreover, these equations cannot represent the relative motion of the sources and the retarded time for the measurement point.