During cystoscopy, the lower pole ureteral orifice was easily visualized, and a left retrograde pyelogram was performed, demonstrating a normal renal unit. A 5 Fr open-ended catheter was placed. The ectopic upper pole ureteral orifice was not visualized despite injection of intravenous indigo carmine. An open RRP was performed using a previously described technique.5 After mobilization of the prostate, the catheter was retracted in a cephalad direction and Denonvilliers fascia overlying the seminal vesicles and vasa was incised and the rectum was bluntly mobilized off these structures. The vasa were ligated and divided and mobilized off the Inhibitors,research,lifescience,medical seminal vesicles.

A third tubular structure was identified lateral to the left seminal vesicle that represented the left upper pole ectopic ureter. The wall of the ectopic ureter was intimately associated with the bladder wall prior to traversing the prostate. The left upper pole ectopic ureter was transected clinical trial approximately 5 cm prior to entering the prostate Inhibitors,research,lifescience,medical and was intubated with a 5 Fr open-ended catheter passed in a retrograde manner. The dissection of the prostate and seminal vesicles was then completed. The ectopic ureter was mobilized with meticulous care to preserve

its blood supply. The left lower pole ureter, Inhibitors,research,lifescience,medical which was previously stented, was identified. A 2-cm longitudinal incision was made in the Inhibitors,research,lifescience,medical lower pole ureter. Both stents were removed. The left upper pole ureter was spatulated, and then anastamosed in an end-to-side fashion to the lower pole segment with a running 5.0 polydioxanone (PDS) suture. Prior to completing the anastomosis, a 5 Fr open-ended stent was placed retrograde into the lower

pole ureter, across the anastomosis, and into the upper ureter. The anastomosis was observed to be watertight with no extravasation. A 26 Fr Malecot catheter was positioned into the bladder through a stab incision Inhibitors,research,lifescience,medical into the dome of the bladder. The vesicourethral anastomosis was performed in the usual fashion over an 18 Fr Foley catheter.5 The ureteral stent and Metalloexopeptidase suprapubic tube were brought out to the skin through separate incisions in the abdominal wall. On pathology examination, the orifice of the ectopic ureter was easily cannulated with a metal probe that traversed through the prostate along the intraprostatic portion of the ureter and exited into the prostatic urethra approximately 5 mm distal to the bladder neck and 3 mm proximal to the utricle (Figure 4A). Blue ink was introduced into the lumen and used to assure identification of the channel on sectioning the prostate. The prostate was sectioned in the standard fashion into transverse slices perpendicular to its long axis. The intraprostatic ureteral channel could be visualized on individual slices (Figure 4).