“BACKGROUND Atypical fibroxanthoma (AFX) and undifferentiated
pleomorphic sarcoma (UPS) are uncommon, spindle cell cutaneous malignancies. Solid organ transplant recipients (SOTRs) are immunosuppressed and therefore have a higher incidence of cutaneous malignancies.
OBJECTIVE We describe the clinical spectrum of AFX and a more-aggressive, deeper variant, UPS, in SOTRs.
MATERIALS AND METHODS A retrospective Ilomastat mouse chart review of AFX and UPS in SOTRs was implemented. Cases from Vanderbilt University, Emory University, Mayo Clinic-Jacksonville, and University of Rochester were included. A literature search included previously published cases.
RESULTS The average age of SOTRs at time of tumor presentation was younger than typically seen in immunocompetent patients for AFX. Rates of local recurrences and metastases were higher in
the SOTRs than is noted in the immunocompetent literature. Rates of recurrence were higher in those treated with excision than in those treated with Mohs micrographic surgery (MMS).
CONCLUSION AFX and UPS may have a greater risk for recurrence, metastases, and mortality in SOTRs, in whom early treatment with MMS may demonstrate certain advantages in terms of minimizing risk of recurrence and metastasis. UPS and recurrent tumors should be staged appropriately and may respond to adjuvant radiation therapy and reduction of MEK pathway immunosuppression. Immunohistochemical evaluation is recommended to exclude other spindle cell tumors.”
“CoSb3 nanocomposites with different contents of CoSb3 nanoparticles were prepared by mixing nanosized CoSb3 particles obtained via polyol method and micron-sized particles obtained via solid state reaction. X-ray diffractometer and field emission scanning electron microscope were used to characterize the prepared products. The thermoelectric properties of the nanocomposites
with different amounts of nanoparticles as dispersants were measured from room temperature to around 500 degrees C. Due to the grain boundaries scattering, the lattice thermal conductivity was observed to decrease as the amount of nanoparticles increased. click here The electrical properties were also improved by the addition of nanoparticles. The ZT value of the nanocomposites with 10 wt % of nanoparticles was nearly doubled that of the sample without any nanoparticles.”
“BACKGROUND Dermatologic surgeons perform numerous procedures that put them at risk of developing work-related musculoskeletal disorders.
OBJECTIVE To study the prevalence of work-related musculoskeletal disorders and role of ergonomics in dermatologic surgery.
METHODS AND MATERIALS A survey study was sent to members of the American College of Mohs Surgery in 2010. The main outcome measures were survey responses relating to surgeon demographics, musculoskeletal symptoms, workstyle habits and attitudes, and ergonomic practices.
RESULTS Ninety percent of respondents reported some type of musculoskeletal symptoms or injuries.