a, LS-4 was
a representative of other six isolates because the same plots were shown for GC-2, ST-7, GCH-3, HM-1, HQ-5, HQ-6 and LS-4. b, VR2332 was a representative of other three reference virus because the same plots were shown for BJ-4 and MLV. (TIFF 128 KB) Additional file 6: Table S4. Estimates of Evolutionary Divergence selleckchem between isolates and references Ferrostatin-1 chemical structure based on gp4 gene Sequences . (DOC 42 KB) Additional file 7: Figure S3. antigenic index analysis: plots of ORF4 generated by the Kyte and Doolittle method. Major areas of difference are indicated by arrows. a, LS-4 was a representative of other five isolates because of the same plots (GCH-3, HM-1, HQ-5, HQ-6 and ST-7). b, BJ-4 was a representative of other two reference virus because the same plots were shown for BJ-4 and MLV. (TIFF 138 KB) Additional file 8: Table S5: Estimates of Evolutionary Divergence between isolates and references based on Nsp2 BAY 11-7082 chemical structure gene Sequences. (DOC 42 KB) Additional file 9: Table S6: prediction of immuno-dominant B-cell epitopes of NSP2 protein. (DOC 40 KB) Additional file 10: Table S7: The information of
seven isolates from pig farms of Shijiazhuang city, in Hebei province. (DOC 50 KB) Additional file 11: Table S8: Summary of the PRRSV analyzed in this study. (DOC 138 KB) References 1. Albina E: Epidemiology of porcine reproductive and Respiratory syndrome (PRRS): an overview. Vet Microbiol 1997, 55:309–316.PubMedCrossRef 2. Wensvoort G, Terpstra C, Pol JM, Ter Laak EA, Bloemraad M, De Kluyver EP: Mystery swine disease in The Netherlands: the isolation of Lelystad virus . Vet Q 1991,13(3):121–130.PubMed 3. Cavanagh D: Nidovirales : a new order comprising Coronaviridae and Arteriviridae . Arch Virol 1997,142(3):629–633.PubMed 4. Gao ZQ, Guo X, Yang HC: Genomic characterization of two Chinese isolates of porcine respiratory and reproductive syndrome virus. Arch
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