This study demonstrates the potential usefulness of natural antioxidants extracted from barley husks in the development of active packaging films for food preservation. (C) 2010 Elsevier Ltd. All rights reserved.”
“Urinary incontinence is common among women, and these individuals may have different perceptions about sensitive skin than the general population.
We used an epidemiological approach to determine patterns of perceived sensitive skin among incontinent women. In addition, perceptions Selleckchem VE821 about sensitivity to certain products and environmental factors were evaluated.
A total of 29 women over the
age of 50 suffering from light urinary incontinence filled out questionnaires designed to evaluate perceptions of sensitive skin in general, and at specific body sites (face, body and genital area). Results were compared to age- and gender-matched
control subjects.
A significant difference was found between incontinence and controls for perceived sensitivity in general, however, no significant differences were found for perceived sensitivity at the three specific body sites, i.e., face, body and genital area. The PD173074 in vivo majority of participants in both the control and incontinent groups were fairly consistent with the perception of sensitive skin in general and sensitive skin of the face and body. Both groups were less consistent in describing the skin of the genital area. Responses of the two groups were similar regarding the perception of the certain environmental factors and products cause irritation.
A significantly higher percentage of
subjects with urinary incontinence describe their skin overall as “”sensitive”". Incontinents tended to describe the skin of the genital area as less sensitive than skin overall, whereas the controls tended to the genital area as more sensitive.”
“To check details treat hypertension around 75% of patients will require combination therapy for which administration of lisinopril and indapamide could be of practical use. Lisinopril has a low oral bioavailability (around 25%) with large intersubject variability (6-60%), due to slow absorption. In order to improve drug permeability, encapsulation of the drugs within nanoparticles (NPs) has demonstrated great potential. For this reason we have prepared hard capsules containing both drugs: indapamide and lisinopril-loaded chitosan (CS) nanoparticles. The mucoadhesive characteristics of CS-NPs will prolong the residence time of lisinopril in contact with the intestinal membrane thereby increasing its oral bioavailability. Moreover, for their quantification a reversed-phase HPLC method is developed and validated using a C18 column. The mobile phase is prepared with methanol: water (50: 50, v/v) including triethylamine (0.1% of total volume) and adjusted at pH 3.1. The calibration curves are linear over the ranges 16-24 mu g.mL(-1) for lisinopril and 8-12 mu g.mL(-1) for indapamide. Intra-day precision results in % RSD ranging 0.74-1.